| Autor: |
Ibrahim, Rania S. M., Elzayat, W., Seif, H. M., El-Kiki, H. A., Emad-Eldin, S., Shahin, M., Kamel, S. M., Osama, R., Zakaryia, R., Fatouh, M., Hachem, Rania H. |
| Zdroj: |
Egyptian Journal of Radiology & Nuclear Medicine; 6/26/2020, Vol. 51 Issue 1, p1-11, 11p |
| Abstrakt: |
Background: Acute necrotizing encephalopathy of children (ANEC) is a rare fulminant type of acute encephalopathy that mainly occurs in children with a characteristic clinico-radiological pattern. It is commonly preceded by viral infections. The condition carries a poor prognosis with high morbidity and mortality rates. We highlight the relationship between diagnostic multi-parametric magnetic resonance imaging (MRI) findings and correlate them with the clinical outcome of children with ANEC by enrollment of MRI scoring. Results: The thalami were involved in all 30 patients, brain stem in 80%, basal ganglia (13.3%), cerebral white matter (WM) in 73%, and cerebellar WM in 33%. Hemorrhage was present in 86.7% patients, edema 80%, and necrosis in 13.3%. We found that the patients having the highest MRI scores were in the poor outcome category; whereas the patients with lower MR score (1 or 2) had better outcomes. Statistically positive correlation (r= 0.1198) was found between the multi-parametric MR score and the outcome category. Conclusion: An extended multi-parametric MRI should be performed in ANEC, allowing early detection and scoring of the disease for better prognosis. There is a positive correlation between the clinical outcome and the MR scoring. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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