COMPARISON BETWEEN THE DIRECT CAPILLARY TUBE LEUCOCYTE MIGRATION TECHNIQUE (LMCT) AND THE DIRECT AGAROSE LEUCOCYTE MIGRATION TECHNIQUE (LMAT) AS INDICATORS OF TUMOUR-DIRECTED CELL-MEDIATED HYPERSENSITIVITY (TCMH) IN PATIENTS WITH RENAL CARCINOMA.

Autor: Kjaer, Mogens, Sørensen, Torben B.
Zdroj: Acta Allergologica; Apr76, Vol. 31 Issue 2, p141-158, 18p
Abstrakt: A comparison was made between the direct capillary tube leucocyte migration technique (LMCT) and the direct agarose leucocyte migration technique (LMAT) using crude homogenates of tumour tissue as antigen in patients with renal carcinoma. A state of specifically altered reactivity of leucocytes from patients with renal carcinoma as compared with normal control persons towards allogeneic hypernephroma extracts could be detected in the LMCT but not in the LMAT. The reactivity in the LMCT was manifest at protein concentrations of 300 and 400 μg/ml. The study indicates that in contrast to the LMCT, the LMAT cannot be used for detection of TCMH towards allogeneic hypernephroma tissue extracts in patients with renal carcinoma. [ABSTRACT FROM AUTHOR]
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