Primary intraosseous carcinoma of the maxilla arising from an odontogenic keratocyst: a case report and review of the literature.

Autor: Gonçalves, Jussara Maria, Godoi Marola, Luiz Henrique, Modolo, Filipe, Couto Vieira, Daniella Serafin, de Los Santos, Gustavo Philippi, Esquiche León, Jorge, Gondak, Rogério
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Zdroj: General Dentistry; Nov/Dec2019, Vol. 67 Issue 6, p26-33, 8p
Abstrakt: A 47-year-old man was referred for treatment of a painful lesion of 5 months' duration located on the left side of the maxilla. A small perforation in the buccal cortex was observed during the intraoral examination. Cone beam computed tomography (CBCT) showed an extensive, well-delimited radiolucent lesion extending from the alveolar ridge to the nasal cavity. An incisional biopsy was performed, and a cystic lesion consistent with an odontogenic keratocyst (OKC) was observed microscopically. The initial treatment option was decompression to be followed by enucleation. However, 3 months after decompression of the lesion, the patient returned because there was a significant increase in the size of the perforation. A destructive lytic lesion that involved the left side of the maxilla and crossed the midline was evident in the CBCT. The examination of a second incisional biopsy specimen showed epithelial neoplasia comprising islands and projections toward the surface. There was abundant keratin deposition, resulting in the formation of pearls and plugs. A diagnosis of primary intraosseous carcinoma arising from an OKC was confirmed, and the patient underwent a maxillectomy. After 1 year of followup, there were no signs of recurrence. [ABSTRACT FROM AUTHOR]
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