| Autor: |
Domnisor, L., Tacu, D., Bucsa, C., Tincu, C., Gingu, C., Baston, C., Harza, M., Manea, I., Preda, A., Sorohan, B., Ismail, G., Sinescu, I. |
| Předmět: |
|
| Zdroj: |
Romanian Journal of Urology; 2018, Vol. 17 Issue 4, p9-13, 5p |
| Abstrakt: |
Introduction and Objectives. In the era of increased need for kidney allografts, it is essential to identify predictors of graft dysfunction after kidney transplantation. Delayed graft function (DGF) is the most common form of acute kidney injury diagnosed in the first week following kidney transplantation that is frequently associated with a negative impact on short-term and long-term allograft function. This study aimed to determine the risk factors influencing DGF after deceased donor kidney transplantation in our center. Materials and Methods. In this prospective study we enrolled 116 recipients of kidney grafts transplanted from deceased donors between January and December 2014 in the Center of Uronephrology and Renal Transplantation, Fundeni Clinical Institute. Our kidney transplant center team consisted of experts in transplant surgery, nephrology and anesthesiology was involved in all steps of transplantation. The endpoint of our study was DGF which was defined as the need for dialysis within the first 7 days after kidney transplantation. Results. Incidence of DGF was 12.9%. Recipient cardiac heart failure (CHF) was the only independent risk factor for DGF. Moreover, by multivariate analysis, CHF significantly increased the risk of DGF by 7.4 times (OR=7.39; 95% CI 1.57- 34.63, p=0.01). Recipient weight and cold ischemia time > 12 h presented a statistical trend of association with DGF. Conclusions. In our study, recipient weight and recipient CHF were the most important risk factor associated with DGF, highlighting the importance of recipient characteristics for a successful kidney transplant. Moreover, prolonged CIT presented a trend association with DGF, underlining the importance of logistic period until reimplantation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
