Effects of Quercitrin on Diabetic Physiological Criterions and Hematological Parameters Studied in Diabetic Rats.

Autor:	Mahadeva Rao US
Zdroj:	International Medical Journal; Aug2019, Vol. 26 Issue 4, p266-269, 4p
Abstrakt:	Objective: To investigate the diabetic physiological criterions pertaining to antihyperglycemic properties of quercitrin (Qn) and its beneficial effect on hematological parameters in streptozotocin (STZ) induced diabetic rats. Methods: Diabetes (DM) was induced in male Wistar rats by STZ. After being confirmed diabetic, animals were orally treated with distilled water or Qn 7.5 mg/kg body weight/rat/day for 10 days. The hematological parameters including RBC and WBC cells and their functional indices were evaluated in diabetic treated groups compared with the controls. Results: Qn significantly reduced the blood glucose levels. The feed and water intake in DM rats were significantly reduced while weight loss was minimized after Qn administration. Equally, the levels of RBC and WBC and their functional indices were significantly improved after Qn administration. Conclusion: It is hypothesized that Qn possesses antihyperglycemic properties and prevents secondary complications of DM as well as improving some hematological parameters. [ABSTRACT FROM AUTHOR]
Databáze:	Supplemental Index
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