Prevalence of vitamin Ddeficiency and its relationship with factors associated with recurrent wheezing.

Autor: Peçanha, Mirna Brito, de Barros Freitas, Rodrigo, Moreira, Tiago Ricardo, Silva, Luiz Sérgio, de Oliveira, Leandro Licursi, Cardoso, Silvia Almeida
Předmět:
Zdroj: Brazilian Journal of Pulmonology / Jornal Brasileiro de Pneumologia; jan/feb2019, Vol. 45 Issue 1, p1-6, 6p
Abstrakt: Objective: To determine the prevalence of vitamin D deficiency/insufficiency in children 0-18 years of age with recurrent wheezing and/or asthma residing in the microregion of Viçosa, Minas Gerais, Brazil, and treated at a referral center, and to determine its association with major risk factors for wheezing. Methods: A cross-sectional study was performed using a semi-structured questionnaire, which was administered by trained interviewers to the legal guardians of the study participants. Data were obtained regarding general characteristics of recurrent wheezing; general sociodemographic, environmental, and biologic factors; and atopy-related factors. The magnitude of the statistical association was assessed by calculating ORs and their corresponding 95% CIs by using multiple logistic regression. Results: We included 1 24 children in the s tudy. The prevalence of vitamin D deficiency/insufficiency in the sample was 57.3%. Vitamin D deficiency/insufficiency was found to be associated with wheezing in the first year of life, personal history of atopic dermatitis, environmental pollution, and vitamin D supplementation until 2 years of age. Conclusions: The prevalence of vitamin D deficiency/insufficiency was high in our sample. Vitamin D concentrations were directly associated with vitamin D supplementation until 2 years of age and were inversely associated with wheezing events in the first year of life, personal history of atopic dermatitis, and environmental pollution. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index