| Autor: |
Xu, Jiake, Wang, Yanpeng, He, Jing, Xia, Weichun, Zou, Yan, Ruan, Wencong, Lou, Qi, Li, Ying, Li, Haifeng, Chen, Wei |
| Zdroj: |
Stem Cell Research; Mar2019, Vol. 35, p101407-101407, 1p |
| Abstrakt: |
Abstract The human iPSC cell line ZJUCHi001-A was established from renal epithelial cells present in urine (urinary cells) harvested from a 2-year-old Charcot-Marie-Tooth disease type 1B (CMT1B) patient carrying point mutation in MPZ (c.292C>T). Urinary cells were reprogrammed by retrovirus vectors containing reprogramming factors: OCT4, SOX2, KLF4 and c-MYC. The pluripotency, capacity of differentiation into 3 germ layers, silence of reprogramming factors and normal karyotype for this cell line were all confirmed in this study. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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