| Autor: |
El-Esawy, B. H. U., Dahlawi, H., Alsharef, K., Shafie, A., El-missbah, T. E., Raafat, B. M., El-Askary, A., Mehanna, O. |
| Zdroj: |
International Medical Journal; Dec2018, Vol. 25 Issue 6, p378-381, 4p |
| Abstrakt: |
Introduction: Primary intestinal lymphoma is defined as an extranodal lymphoma arising in the intestine. Objectives: The aim of this study was to evaluate the clinicopathological & immunophenotypic characteristics of non-Hodgkin's primary intestinal lymphoma (NHL). Materials and Methods: 125 cases of spare primary intestinal non-Hodgkin lymphoma were studied retrospectively in a 5 year period. 90 cases were from large intestine & 35 cases were from small intestine. Hematoxylin and eosin stained sections were studied by light microscopy and immunohistochemistry for CD3, CD20 Bcl2 and cyclin D1 were done to confirm the histopathological diagnosis. All cases were reclassified according to the World Health Organization classification of lymphoma in 2008. Results: Primary intestinal lymphomas were more common in the large intestine, the caecum is commonly affected with male preponderance, advanced stage & mean age of 47 ² 9 year. Abdominal pain and abdominal mass were two common presenting symptoms. B-cell phenotype represented by 105 case (84%) with the commonest variant DLBCL (59%) while T-cell phenotype represented by 15 case (12%) with PTCL is the commonest type (8%) and unclassifiable type was 5 cases (4%). Conclusion: Primary intestinal lymphoma is a heterogeneous entities and due to the lack of specific clinical symptoms and low incidence, primary intestinal lymphoma is misdiagnosed until serious complications occur and hence needs to be accurately diagnosed earlier. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
