| Autor: |
Khedr, Eman M., Fawi, Gharib, Abbas, Mohammed Abd Allah, Mohammed, Talal A., El-Fetoh, Noha Abo, Attar, Ghada Al, Zaki, Ahmed F. |
| Předmět: |
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| Zdroj: |
Neurological Research; Jul2015, Vol. 37 Issue 7, p607-618, 12p |
| Abstrakt: |
Background and purpose: In a previous study we found a high crude prevalence rate (CPR) for Parkinson's disease (PD) in Assiut governorate/Egypt. We therefore surveyed a second Nile valley governorate (Qena) to provide confirmatory evidence for the high prevalence rate of PD in Egypt. Subjects and methods: 10 areas in Qena governorate were selected by random sampling to recruit 8027 inhabitants. Positive cases were identified using a modified screening questionnaire, the unified Parkinson disease rating scale (UPDRS), mini-mental state examination (MMSE) and the non-motor symptoms scale (NMSS) for PD. Results: Forty-four patients were identified with Parkinsonism, giving a CPR of 548/105 inhabitants. Among them, 35 patients were diagnosed as PD with CPR of 436/105; three cases were diagnosed as drug-induced Parkinsonism with CPR 37/105; two cases had atherosclerotic Parkinsonism with CPR 25/105.Age-specific CPR of PD among population aged ≥ 50 years old was 2534/105.The highest age-specific CPR was recorded among subjects ≥ 75 years old. The CPR showed a tendency to be higher in males than females, urban than rural areas and industrial than non-industrial areas (503 vs 363/105, 474 vs 389/105 and 655 vs 312/105, respectively). There was a significantly higher CPR among illiterate than literate persons (1982 vs 299/105 with P = 0.00001). About one quarter of patients had cognitive impairment. All cases had positive symptoms in at least one or more NMS Domains. Conclusion: The overall prevalence of PD disease is high in Nile valley governorates of Upper Egypt compared to other Arabic countries. [ABSTRACT FROM AUTHOR] |
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