Fish oil supplemental dose needed to reach 1 g% DHA+EPA in mature milk.

Autor: Stoutjesdijk, E., Schaafsma, A., Dijck-Brouwer, D.A.J., Muskiet, F.A.J.
Zdroj: Prostaglandins Leukotrienes & Essential Fatty Acids; Jan2018, Vol. 128, p53-61, 9p
Abstrakt: Introduction Erythrocyte (RBC) DHA+EPA is considered optimal at 8 g%. Mothers with lifetime high fish intakes exhibiting this status produce milk with about 1 g% DHA+EPA. We established DHA+EPA supplemental dosages needed to augment RBC DHA+EPA to 8 g% and milk DHA+EPA to 1 g%. Materials and methods Pregnant women were randomly allocated to DHA+EPA dosages of: 225+90 (n=9), 450+180 (n=9), 675+270 (n=11) and 900+360 (n=7) mg/day. Samples were collected at 20 and 36 gestational weeks and 4 weeks postpartum. Results Linear regression revealed needed dosages rounded at 750 mg/day to reach 8 g% RBC DHA+EPA and 1000 mg/day for 1 g% milk DHA+EPA. RBC DHA+EPA increment depended on baseline values. There was no effect on milk AA, but milk EPA/AA ratio increased. Conclusion Women with an RBC DHA+EPA status of 5.5 g% need 750 and 1000 mg DHA+EPA/day to reach 8 g% RBC DHA+EPA at the pregnancy end and 1 g% mature milk DHA+EPA, respectively. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index
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