Preparation of blue-color-emitting graphene quantum dots and their in vitro and in vivo toxicity evaluation.

Autor:	Nafiujjaman, Md, Kim, Jeongho, Park, Hun-Kuk, Lee, Yong-Kyu
Předmět:	QUANTUM dots spectra ORGANIC synthesis OVARIAN epithelial cancer CELL survival ERYTHROCYTES PHYSIOLOGY
Zdroj:	Journal of Industrial & Engineering Chemistry; Jan2018, Vol. 57, p171-180, 10p
Abstrakt:	We synthesized and characterized blue-color-emitting graphene quantum dots (BGQDs) which is better than that of other GQDs synthesized from organic molecules. We investigated the biocompatibility of BGQDs with cells and erythrocytes. Evaluation of epithelial carcinoma cancer cells indicated that most cells successfully took up BGQDs and toxicity testing showed no effect on cell viability. We also examined alterations in deformability and aggregation of human erythrocytes exposed to BGQDs at different concentrations and incubation times. These results suggest that BGQDs are biocompatible and do not cause cell membrane damage, and thus, are promising nanomaterials for various medical diagnoses and treatments. [ABSTRACT FROM AUTHOR]
Databáze:	Supplemental Index
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect