Premature rupture of membranes at 34 to 37 weeks' gestation: aggressive versus conservative management.

Autor:	Naef, R W 3rd, Allbert, J R, Ross, E L, Weber, B M, Martin, R W, Morrison, J C
Předmět:	TREATMENT of pregnancy complications CLINICAL trials COMPARATIVE studies DISEASES FETAL diseases FETAL ultrasonic imaging GESTATIONAL age LENGTH of stay in hospitals INDUCED labor (Obstetrics) NEONATAL diseases LONGITUDINAL method RESEARCH methodology MEDICAL care EVALUATION of medical care MEDICAL cooperation OXYTOCIN PATIENTS PREGNANCY THIRD trimester of pregnancy RESEARCH UTERINE contraction EVALUATION research RANDOMIZED controlled trials OXYTOCICS PHARMACODYNAMICS PREVENTION
Zdroj:	American Journal of Obstetrics & Gynecology; Jan98 Part 2 of 2, Vol. 178 Issue 1, p126-130, 5p
Abstrakt:	Objective: Our purpose was to compare induction of labor with preterm rupture of membranes between 34 and 37 weeks' gestation with expectant management.Study Design: In this prospective investigation 120 gravid women at > or = 34 weeks 0 days and < 36 weeks 6 days of gestation were randomized to receive oxytocin induction (n = 57) or observation (n = 63).Results: Estimated gestational age at rupture of membranes (34.3 +/- 1.4 weeks vs 34.5 +/- 1.4 weeks) and ultrasonographically estimated fetal weight (2230 +/- 321 gm vs 2297 +/- 365 gm) were equivalent between groups (not significant). Chorioamnionitis occurred more often (16% vs 2%, p = 0.007), and maternal hospital stay (5.2 +/- 6.8 days vs 2.6 +/- 1.6 days, p = 0.006) was significantly longer in the control group. Neonatal sepsis was also more common in the observation group (n = 3) than among induction patients (n = 0), but the difference was not statistically significant.Conclusion: Aggressive management of preterm premature rupture of the membranes at > or = 34 weeks 0 days of gestation by induction of labor is safe for the infant in our population and avoids maternal-neonatal infectious complications. [ABSTRACT FROM AUTHOR]
Databáze:	Supplemental Index
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