| Autor: |
P., Risti Saptarini, Riyanti, Eriska, Sufiawati, Irna, Azhari, Sasmita, Inne S. |
| Předmět: |
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| Zdroj: |
Journal of International Dental & Medical Research; 2017, Vol. 10 Issue 2, p313-317, 5p, 3 Black and White Photographs, 1 Chart |
| Abstrakt: |
Human immunodeficiency virus (HIV) is a virus attacking the immune system of the body, usually was caused by HIV type 1. The proportion of women in new HIV infections in Indonesia has grown from 34 percent in 2008 to 44 percent in 2011 will lead a rise infections among children. There is an association between low vitamin D and HIV disease progression. Vitamin D is not only involved in calcium homeostasis which has a negative impact on bone health, but also in the regulation of the immune system. Bone alteration has been observed in the course of HIV which reduced bone mineral density is the bone alteration found in HIV patients. Bone mineral density is a parameter that predicts fracture risk which in turn correlates with a shorter life expectancy. This research will study the level vitamin D and calcium serum with mandibular bone density in HIV/AIDS children. The research method is cross-sectional study, serum 1,25-dihydroxyvitamin D and calcium levels were assessed from blood for the randomly selected subject of HIV-infected children enrolled treatment at Clinic Teratai FKUP Rumah Sakit Hasan Sadikin Bandung, West Java, Indonesia during March-June 2015. A panoramic radiograph was taken for measuring mandibular bone density. All 40 subject HIV/AIDS children showed serum 1,25-dihydroxyvitamin D were classified as vitamin D deficient (≤ 20nm/ml). A few subject showed an insufficient serum calcium level and 70%patient has low mandibular bone density. Deficient vitamin D levels may lead lower mandibular bone density in HIV/AIDS children. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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