Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities.

Autor: Weiss, Matthew M., Dineen, Thomas A., Marx, Isaac E., Altmann, Steven, Boezio, Alessandro, Bregman, Howard, Chu-Moyer, Margaret, DiMauro, Erin F., Feric Bojic, Elma, Foti, Robert S., Hua Gao, Graceffa, Russell, Gunaydin, Hakan, Guzman-Perez, Angel, Hongbing Huang, Liyue Huang, Jarosh, Michael, Kornecook, Thomas, Kreiman, Charles R., Ligutti, Joseph
Zdroj: Journal of Medicinal Chemistry; 7/27/2017, Vol. 60 Issue 14, p5969-5989, 21p
Databáze: Supplemental Index