Practical Synthesis of MDM2 Antagonist RG7388. Part 2: Development of the Cu(I) Catalyzed [3 + 2] Asymmetric Cycloaddition Process for the Manufacture of Idasanutlin.

Autor: Rimmler, Gösta, Alker, Andre, Bosco, Marcello, Diodone, Ralph, Fishlock, Dan, Hildbrand, Stefan, Kuhn, Bernd, Moessner, Christian, Peters, Carsten, Rege, Pankaj D., Schantz, Markus
Zdroj: Organic Process Research & Development; 12/16/2016, Vol. 20 Issue 12, p2057-2066, 10p
Databáze: Supplemental Index