| Autor: |
Eslami, Hosein, Pakdel, Farzaneh, Babaloo, Zohreh, Pouralibaba, Firouz, Falsafi, Parisa, Neghad, Sahar Khadem, Pakdel, Mehdi Vahid, Fakhrzadeh, Vahid |
| Předmět: |
|
| Zdroj: |
International Journal of Clinical Dentistry; 2016, Vol. 9 Issue 4, p241-245, 5p |
| Abstrakt: |
Background and aim: The etiology of Oral Lichen Planus (OLP) is not known, autoreactive T lymphocytes may being involved in the pathogenesis of OLP. We aimed in this study to investigate the relationship between Interleukin-8 (IL-8) and Interleukin-1B (IL-1B) levels and disease activity in the patients suffering from OLP. Materials and methods: This descriptive analytical study included 56 patients with OLP and 50 healthy control individuals. Blood samples were obtained from both subjects. Serum IL-8 and IL-1B was determined by ELISA kit. Results: The Level of IL-8 (168.23 ± 33.2) and IL-1B (174.18 ± 23.2) were higher in OLP patients in comparison to healthy control group, respectively (P=0.004 and P < 0.001). Conclusions: The high levels of IL-1B and IL-8 in OLP patients indicate the role of immunity in the development of the disease. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
