Using Crossmatch Tests for Serological Compatibility Assessment Intra-And Interspecific at Dogs and Cats.

Autor: MUNTEAN, Sergiu, ŞTEFĂNUŢ, Cristina, DRĂGAN, Rareş, BARABÁSI, Ildikó, OGNEAN, Laurenţ
Předmět:
Zdroj: Bulletin of the University of Agricultural Sciences & Veterinary Medicine Cluj-Napoca. Veterinary Medicine; 2016, Vol. 73 Issue 2, p394-398, 5p
Abstrakt: Selecting compatible blood is essential for the safety and efficiency of transfusion therapy. Correct performing and repeating Crossmatch tests can prevent immediate and delayed immune reactions caused by sensitization of subjects. In the cats' case, it is called into question solving low availability of sources of compatible blood donors by using canines. The aim was to comparatively analyze serological intraspecific and interspecific compatibility on samples of dogs and cats in order to evaluate the possibility of implementing transfusion therapy with canine blood to feline subjects. There were conducted Crossmatch tests on blood samples (n=42) collected on anticoagulant substance from dogs (n=36) and cats (n=6) from the FMV Cluj-Napoca clinics. There were performed 156 Crossmatch tests, predominantly through quick technique on smears and in some cases (15%) the method based on separating the plasma and preparing hematies suspension. Intraspecific compatibility on dogs was predominantly negative. Remarkable is the case of a canine patient on which we registered all 24 Crossmatch major tests high positive intensity (3+), without a historical therapy with blood products. Regarding the intraspecific compatibility tests, all the xenocompatibility dog-cat tests showed high positive reactions, both for major and minor Crossmatch (3+/4+). The intraspecific compatibility at dogs is very high before the first contact with blood products, without excluding the possibility of some atypical sensitivization for clinical interest. The evaluation of the post-transfusional risk. Regarding the interspecific compatibility dog-cat, all the tests were highly positive and we can not sustain a probable xenotransfusion. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index