Efficacy of Different Drugs in the Management of Congestive Heart Failure Related to Dilated Cardiomyopathy in Dogs.

Autor: sree, K. Usha, Rao, V. Vaikunta, kumari, K. Nalini, Prameela, D. Rani
Předmět:
Zdroj: Indian Veterinary Journal; Nov2016, Vol. 93 Issue 11, p13-15, 3p, 3 Charts
Abstrakt: Dogs with dilated cardiomyopathy (DCM) were randomly allotted to two treatment groups. Dogs in group-I are treated with Digoxin-0.22 mg/m2 twice daily, Enalapril-0.5 mg/kg b.wt daily, Furosemide-2mg/kg b.wt twice daily orally. Dogs in group-II were treated orally with L-Carnitine-50 mg/kg b.wt and Tab Abana 250 mg/dog twice daily. Therapeutic efficacy of drugs was made on the basis of comparative assessment of m-mode left ventricular contractility indices between dogs of group-I and group-II on zero and forty five days post treatment. The post treatment values of fractional shortening (FS) and Ejection fraction (EF) among Group-I and group-II were statistically not significant. In group-I after forty five days of treatment there was incidence of azotemia, whereas in group-II there was no incidence of azotemia that might be due to added cardioprotective effect of L-Carnitine and Abana. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index