Inhibition of Chromosome Separation in Fertilized Starfish Eggs by Kalihinol F, a Topoisomerase I Inhibitor Obtained from a Marine Sponge.

Autor: Ohta, Emi, Ohta, Shinji, Hongo, Tomokatsu, Hamaguchi, Yukihisa, Andoh, Toshiwo, Shioda, Masaki, Ikegami, Susumu
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Zdroj: Bioscience, Biotechnology & Biochemistry; Nov2003, Vol. 67 Issue 11, p2365-2372, 8p, 3 Graphs
Abstrakt: Studies Kalihinol F, a naturally occurring diterpene from a marine sponge, Acanthella sp. Result of the inhibited chromosome separation in fertilized starfish eggs; Processes involved in the cell cycle progression; Essential role of topoisomerase I in meiosis II of this species.
Databáze: Supplemental Index