Fluorescence-based assay aids screening of potential HIV RT RNase H inhibitors.
| Zdroj: | Biotech Week; 12/10/2003, p679-679, 1p |
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| Abstrakt: | A novel fluorescence-based assay may aid the search for agents that can suppress HIV RT ribonuclease H (RNase H) activity. In a recent study from the United States, "A fluorescence resonance energy transfer assay readily applicable to 96-well and 384-well microplate formats with robotic operation was developed to enable high-throughput screening for inhibitors of HIV-1 reverse transcriptase-associated RNase H activity, an underexplored target for antiretroviral development." |
| Databáze: | Supplemental Index |
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