Effect of methotrexate on cerebellar development in infant rats.

Autor: Akihiko SUGIYAMA, Jing SUN, Kota UEDA, Satoshi FURUKAWA, Takashi TAKEUCHI
Předmět:
Zdroj: Journal of Veterinary Medical Science; Jul2015, Vol. 77 Issue 7, p789-797, 9p
Abstrakt: The article presents a study on the effect of methotrexate (MTX) on the cerebellar development in infant rats. Topics include the treatment of 6-day-old rats with intraperitoneal methotrexate injections and an examination of the cerebellum, a comparison of the results between the methotrexate-treated group with a control group in various days after treatment (DAT), and how MTX exposure on postnatal day 6 results in cerebellar hypoplasia.
Databáze: Supplemental Index