Discovery of 1-{4-[3-Fluoro-4-((3S,6R)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C (RORc or...

Autor: Benjamin P. Fauber, Olivier René, Yuzhong Deng, Jason DeVoss, Céline Eidenschenk, Christine Everett, Arunima Ganguli, Alberto Gobbi, Julie Hawkins, AdamR. Johnson, Hank La, Justin Lesch, Peter Lockey, Maxine Norman, Wenjun Ouyang, Susan Summerhill, Harvey Wong
Zdroj: Journal of Medicinal Chemistry; Jul2015, Vol. 58 Issue 13, p5308-5322, 15p
Databáze: Supplemental Index