Neuropharmacological therapy of the neuroendocrine carcinoid syndrome: report of two cases.

Autor: Lechin F, van der Dijs B, Orozco B, Rodríguez S, Baez S
Zdroj: Journal of Applied Research; Spring2005, Vol. 5 Issue 1, p109-114, 6p
Abstrakt: We discuss two cases of patients affected by the carcinoid syndrome who showed adrenal over neural sympathetic predominance and a TH-2 immunological profile. Both received neuropharmacological therapy addressed to reverting this autonomic nervous system imbalance. Clinical, autonomic nervous system and immunological improvements were registered as of the first 4-week posttreatment period. No relapses have been recorded up to the present (4 and 3 years later, respectively). The neuropharmacological therapy addressed to enhancing central nervous system-noradrenergic activity, which is able to revert adrenal over neural sympathetic predominance, seems to be a valuable tool in treating patients affected by carcinoid syndrome.The fact that patients affected by carcinoid presented common neuroautonomic disorders led us to prescribe the neuropharmacological therapy addressed to revert that abnormal profile. Although we have assessed several of the above-mentioned patients, we refer here only to these two well-investigated, treated, and followedup patients. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index