Ibutilide therapy for atrial fibrillation: 5-year experience in a community hospital.

Autor: Giudici MC, Fischer WJ III, Cervantes DC, Schrumpf PE, Paul DL, Sentman KE, Serra VL, Barold SS
Zdroj: Journal of Cardiovascular Nursing; Nov/Dec2008, Vol. 23 Issue 6, p484-488, 5p
Abstrakt: Many institutions restrict the use of ibutilide because of the potential risk of polymorphic ventricular tachycardia (PMVT). Over a 5-year period from June 2000 to May 2005, 238 patients, 151 men and 87 women, with a mean age of 67.1 years (range, 22-94 years), received intravenous ibutilide at our institution. Ibutilide was administered by nurses or physicians in 4 clinical settings: emergency department (n = 80), intensive care unit (n = 11), patient room on telemetry (n = 107), and in the cardiac catheterization/electrophysiology laboratory (n = 40). Conversion to sinus rhythm occurred in 59% of patients outside the catheterization/electrophysiology laboratory. The incidence of PMVT was 1.7%. Three patients had brief nonsustained PMVT and 1 patient had a sustained PMVT. There was no difference in outcome whether a physician was present at the time of ibutilide administration. Our data suggest that ibutilide is a safe and efficacious drug when ordered by experienced physicians in properly selected patients in a variety of monitored settings. [ABSTRACT FROM AUTHOR]
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