Replacement of the condyle and ascending ramus by a modular endoprosthesis in Macaca fascicularis-part 2: microcomputed tomographic and histologic evaluation of the ramus and stem.

Autor: Goh BT, Lee S, Tideman H, Jansen JA, Stoelinga PJ, Goh, Bee Tin, Lee, Shermin, Tideman, Henk, Jansen, John A, Stoelinga, Paul J W
Zdroj: Journal of Oral & Maxillofacial Surgery (02782391); Dec2009, Vol. 67 Issue 12, p2617-2626, 10p
Abstrakt: Purpose: The present study presents the microcomputed tomographic and histologic evaluation of the peri-implant tissues of a modular endoprosthesis used to replace the condyle and ascending ramus in Macaca fascicularis. Materials and Methods: The right condyle and ascending ramus were resected in 8 adult monkeys and replaced by a modular endoprosthesis, fixed with polymethylmethacrylate bone cement (Palacos). Four monkeys were sacrificed at 3 months and 4 at 6 months postoperatively. Microcomputed tomographic scanning was performed to analyze the bone volume at the bone-cement interface. Histologic and histomorphometric assessments were done using a modified hard and soft tissue grading scale and by studying the total bone contact at the interface. Results: The combined (buccal, lingual, and inferior) mean bone volume percentage of the 6-month group was significantly greater than that of the 3-month group (P < .05). The 6-month specimens showed a reduced inflammatory response and more abundant bone formation around the stem. The total soft tissue histologic score was significantly greater in the 6-month group (P < .05). A total bone contact percentage of 15.4% to 85.2% was achieved in 3 specimens. Conclusions: Satisfactory bone growth was found at the bone-cement interface at the stem region, although direct bone contact with the cement was not achieved in all cases. Soft tissue contact with the prosthetic ramus, in the form of a fibrous capsule, was present in some areas. At 6 months, minimal interfacial inflammation was found in this monkey model. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index