Ineffectiveness of myrrh-derivative Mirazid against schistosomiasis and fascioliasis in humans.

Autor: Osman, M. M., El-Taweel, H. A., Shehab, A. Y., Farag, H. F.
Zdroj: Eastern Mediterranean Health Journal; Sep2010, Vol. 16 Issue 9, p932-936, 5p
Abstrakt: The present study assessed the schistosomicidal and fasciolicidal actions of the myrrh-derivative Mirazid® in an area of low schistosomiasis transmission. A total of 27 patients infected with Schistosoma mansoni and 16 with Fasciola spp. received the maximum recommended dose of Mirazid. Pretreatment egg counts in 4 Kato-Katz slides were compared with similar counts in stool samples collected 1 and 2 months after treatment. Standard procedures and quality control measures were followed. The results revealed that Mirazid used as schistosomicidal or fasciolicidal agent in the maximum recommended dose has a low cure rate and produced a negligible reduction in egg counts. Prescribing such an ineffective drug in Egypt might endanger the achievements of the schistosomiasis control strategy. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index