Human Skeletal Muscle and Subcutaneous Tissue Carbon Dioxide, Nitrogen, and Oxygen Gas Tension Measurements Under Ambient and Hyperbaric Conditions.

Autor: Hart, George B., Wells, Charles H., Strauss, Michael B.
Předmět:
Zdroj: Journal of Applied Research; Spring2003, Vol. 3 Issue 2, p187, 14p
Abstrakt: Objectives: (1) To measure tissue O[2], CO[2], and N[2] tensions in subcutaneous (SQ) and muscle (MM) tissues of the thigh in room air and at two atmospheres absolute (ATA) pressure. (2) To compare the differences in continuous O[2] exposures with O[2] breathing with air breaks under hyperbaric conditions on O[2] and N[2] in MM and SQ tissues. (3) To observe the effect of these exposures on MM and SQ tissue CO[2]s.Method: Gas tensions in resting MM and SQ tissues were recorded at 4-minute intervals during a 3-hour period. Two protocols were compared: protocol A-continuous O[2] breathing in 2 ATA O[2], which represented a monoplace chamber treatment schedule; and protocol B-analogous to a multiplace hyperbaric oxygen treatment with intermittent air breaks between O[2] breathing.Results: Mean room air MM O[2] is 33% less (P < .001) than adjacent SQ O[2], mean MM CO[2] exceeds SQ CO[2] by 13% (P < .001) of the adjacent SQ. Mean MM N[2] tensions are 20% less than the adjacent SQ N[2] tensions (P < .001). Protocol A is superior for reducing MM N[2] (P < .001) compared with protocol B. Muscle O[2] increases more rapidly and to higher levels than the SQ O[2] in protocol B, In protocol A SQ O[2] increases above MM O[2] tensions. Protocol A's SQ O[2] tensions increased 12% more than protocol B. Muscle and SQ CO[2] decrease significantly (P < .001) in 2 ATA O[2] in both protocols.Conclusions: (1) Resting ambient MM N[2] is significantly lower than subcutaneous tissue N[2]. (2) Protocol A is superior for muscle N[2] washout. (3) There are differences in SQ and MM O[2] uptake at 2 ATA as well as differences in uptake between protocols A and B for these tissue compartments. (4) Carbon dioxide decreases in the lower extremity under hyperbaric oxygen conditions. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index