Lead Optimization toward Proof-of-Concept Tools for Huntington’s Disease within a 4-(1H-Pyrazol-4-yl)pyrimidine Class of Pan-JNK Inhibitors.

Autor: John Wityak, Kevin F. McGee, MichaelP. Conlon, Ren Hua Song, Bryan C. Duffy, Brent Clayton, Michael Lynch, Gwen Wang, Emily Freeman, James Haber, Douglas B. Kitchen, David D. Manning, Jiffry Ismail, Yuri Khmelnitsky, Peter Michels, Jeff Webster, Macarena Irigoyen, Michele Luche, Monica Hultman, Mei Bai
Zdroj: Journal of Medicinal Chemistry; Apr2015, Vol. 58 Issue 7, p2967-2987, 21p
Databáze: Supplemental Index