| Autor: |
Grappiolo, Guido, Scardino, Marco, Mazziotta, Giuseppe, Quaini, Stefano, Lodigiani, Corrado, Ferrari, Matteo Carlo |
| Zdroj: |
Italian Journal of Medicine; 2013, Vol. 7 Issue 3, p179-182, 4p, 1 Chart |
| Abstrakt: |
Patients undergoing total hip arthroplasty or total knee arthroplasty have a high risk for post-operative venous thromboembolism. The current study addressed the use of fondaparinux post-operatively in 556 patients with antiplatelet therapy in order to prevent deep vein thrombosis as well as demonstrate efficacy in preventing arterial thrombotic events. Results provided evidence for a safe and effective prophylaxis strategy, involving the change from low molecular weight heparin pre-operatively to fondaparinux post-operatively. Also, fondaparinux proved effective as a unique post-operative therapy in the prevention of venous thromboembolism with no adverse effects, such as major bleeding or arterial thrombosis in patients with pre-operative antiplatelet therapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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