Bromotriphenylphosphonium Salt Promoted One-Pot Cyclization to 2-Fluoroalkyl-Substituted Indoles.

Autor: Zeng-xue Wang, Tai-feng Zhang, Qing-wen Ma, Wei-gui Ni
Předmět:
Zdroj: Synthesis; 2014, Vol. 46 Issue 24, p3309-3314, 6p
Abstrakt: 2-Fluoroalkyl-substituted indoles were prepared in moderate to excellent yields through bromotriphenylphosphonium salt promoted ring formation with fluorine-containing carboxylic acids in the presence of triethylamine in toluene at reflux temperature. A range of 2-fluoroalkyl-substituted indole derivatives can be conveniently prepared. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index