Adenoid cystic carcinoma of palate: Report of a solid variant.

Autor: Srivastava, Anchal, Barpande, S. R., Bhavthankar, J. D., Mandale, M. S.
Předmět:
Zdroj: Journal of Oral & Maxillofacial Pathology (0973029X); 2014 Special Issue, Vol. 18, pS102-S103, 2p
Abstrakt: Introduction: Adenoid cystic carcinomas (AdCCs) are uncommon tumors, comprising less than 1% of all head and neck cancers and 20-25% of all salivary cancers. The most common symptom is a slow growing mass followed by pain due to the propensity of these tumors for perineural invasion. The tumor is most often clinically deceptive by its small size and slow growth, which actually overlies its extensive subclinical invasion and marked ability for early metastasis, making the prognosis questionable, aptly referred to as "wolf in sheep's clothing". Cribriform, tubular and solid are the three recognized histopathologic patterns. One of the important prognostic factors is the histological grade determined by the percentage of solid component in the tumor. Case Report: A 68-year-old male patient reported with a chief complaint of pain on right side of lower jaw, which radiated to right ear since 15 days. Patient also gave history of an ulcer on palate since 1 month. His right submandibular lymph node was enlarged, tender and mobile. Intraoral examination revealed an ulcer 1*1.5 cm in diameter present in posterolateral region of soft palate extending from distal of 15 till tuberosity region. Ulcer extended mesially till midpalatine raphe. Borders were well-defined with rolled out margins. Summary: AdCC with a solid histopathologic pattern are associated with a worse prognosis than those with a cribriform or tubular arrangement; therefore, early detection, prompt treatment and long-term follow-up is essential in clinical management. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index