| Autor: |
Raghini, R., Ravikumar, Renu, Ramani, Pratibha, Natesan, Anuja, Sherlin, Herald, Sukumaran, Gheena |
| Předmět: |
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| Zdroj: |
Journal of Oral & Maxillofacial Pathology (0973029X); 2014 Special Issue, Vol. 18, pS47-S47, 1/4p |
| Abstrakt: |
Background: GLUT-1 also known as glucose transporter member 2, is a uniporter protein, encoded by SLC2 A1 gene. GLUT-1 facilitates the transport of glucose across the plasma membrane. GLUT-1 has received special attention as a sensitive and specific marker of hemangiomas. The high GLUT-1 protein expression in endothelia of hemangiomas reveals the intrinsic characteristics of endothelial phenotypes and permits the distinction from other benign vascular tumors. Aim: To analyze, the immunohistochemical expression of GLUT-1 in diagnosing the vascular hamartomas from other benign vascular tumors. Materials and Methods: Sample size n = 5, concerning with age were retrieved from the archives of the Department of Oral and Maxillofacial Pathology. Immunohistochemistry was done using anti-GLUT-1 antibody and the expression was graded in terms of proportion and intensity. Results and conclusion: The expression of GLUT-1 in vascular hamartomas and its significance shall be discussed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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