Oral candida flora in a group of Indian patients with Thalassemia.

Autor: Shivaratna, M., Gajjada, Nirosha, Prasanna M. D., Surekha, Reddy, Kranthi Kumar
Předmět:
Zdroj: Journal of Oral & Maxillofacial Pathology (0973029X); 2014 Special Issue, Vol. 18, pS45-S45, 1/4p
Abstrakt: Background: Thalassemia constitutes large group of immune-compromised patients in our country with multiple hematological, immunological and endocrine disorders making them susceptible to local and systemic opportunistic yeast infections. Candida constitutes the main yeast flora in oral cavity. Objectives: The aim of the study is to determine the prevalence of oral candidiasis in patients with thalassemia through colonization and speciation. Materials and Methods: The study group consisted of 30 patients diagnosed with thalassemia and 30 age- and sex-matched healthy controls. The samples were collected using concentrated oral rinse technique and then streaked onto plates of Sabouraud's dextrose agar and incubated at 37°C for 48h. The isolates were then subjected for speciation with Hi-chrome agar. Statistical Method: Pearson's chi-square test is used. Results: The mean Candida count was significantly higher in thalassemia patients compared with the healthy group. In patients with age group of 0-5years and 11-15years, there is a significant increase in Candida count. Conclusion: The prevalence of oral candidiasis in a group of Indian population with thalassemia is significantly less when compared to Western population. Among the positive cases, oral candidiasis is comparatively more in the age group of 0-5 years emphasizing the need of oral prophylaxis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index