cAMP-dependent protein kinase phosphorylates and activates nuclear Ca2+-ATPase.

Autor: Rogue, Patrick J., Humbert, Jean-Paul, Meyer, Alphonse, Freyermuth, Solange, Krady, Marie-Marthe, Malviya, Anant N.
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 08/04/98, Vol. 95 Issue 16, p9178, 6p, 1 Color Photograph, 1 Black and White Photograph, 2 Charts, 5 Graphs
Abstrakt: Presents a study which investigated how crosstalk between Ca2+- and cAMP-dependent signaling pathways regulates the transport of macromolecules into the nucleus. Methodology used in the study; Effect of protein kinase (PKA) on nuclear Ca2+-ATPase; How PKA phosphorylation of NCA leads to stimulation of ATP-dependent Ca2+-uptake into the nucleus.
Databáze: Complementary Index