| Autor: |
Cannon, Daniel T., Bimson, William E., Hampson, Sophie A., Bowen, T. Scott, Murgatroyd, Scott R., Marwood, Simon, Kemp, Graham J., Rossiter, Harry B. |
| Předmět: |
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| Zdroj: |
Journal of Physiology; Dec2014, Vol. 592 Issue 23, p5287-5300, 14p |
| Abstrakt: |
Key points Heavy-intensity exercise causes a progressive increase in energy demand that contributes to exercise limitation., This inefficiency arises within the locomotor muscles and is thought to be due to an increase in the ATP cost of power production; however, the responsible mechanism is unresolved., We measured whole-body O2 uptake and skeletal muscle ATP turnover by combined pulmonary gas exchange and magnetic resonance spectroscopy during moderate and heavy exercise in humans., Muscle ATP synthesis rate increased throughout constant-power heavy exercise, but this increase was unrelated to the progression of whole-body inefficiency., Our data indicate that the increased ATP requirement is not the sole cause of inefficiency during heavy exercise, and other mechanisms, such as increased O2 cost of ATP resynthesis, may contribute., Abstract During constant-power high-intensity exercise, the expected increase in oxygen uptake ( [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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