Autor: |
Khavinson, V., Lin'kova, N., Evlashkina, E., Durnova, A., Kozlov, K., Gutop, O. |
Předmět: |
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Zdroj: |
Bulletin of Experimental Biology & Medicine; Nov2014, Vol. 158 Issue 1, p159-163, 5p |
Abstrakt: |
We studied molecular mechanisms of the vasoprotective effects of tripeptide T-38 and dipeptide RR-1. Short peptides T-38 and the RR-1 activate the processes of cell renewal in organotypic and dissociated cultures of vascular cells during aging by increasing the expression of Ki-67 and reducing the synthesis of p53 protein. T-38 and RR-1 reduce the synthesis of E-selectin, adhesion molecule involved in the formation of atherosclerotic plaques. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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