| Autor: |
Lanza ‐ Perea, M., Zieger, U., Qurollo, B.A., Hegarty, B.C., Pultorak, E.L., Kumthekar, S., Bruhl ‐ Day, R., Breitschwerdt, E.B. |
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| Zdroj: |
Journal of Veterinary Internal Medicine; Nov2014, Vol. 28 Issue 6, p1702-1707, 6p |
| Abstrakt: |
Background Frequent exposure of Grenadian dogs to Rhipicephalus sanguineus results in Anaplasma platys, and Ehrlichia canis seroreactivity. During elective surgeries, substantial intraoperative hemorrhage occurs in some seroreactive dogs. Objectives To assess hemostatic parameters and bleeding tendencies as well as prevalence of PCR positivity in apparently healthy A. platys and E. canis seroreactive and seronegative free-roaming dogs from Grenada. Animals Forty-seven elective surgery dogs allocated to 4 groups: Seronegative control (n = 12), A. platys (n = 10), E. canis (n = 14) and A . platys, and E. canis (n = 11) seroreactive. Methods Preoperatively, hemostasis was assessed by platelet count, prothrombin time, activated partial thromboplastin time, and buccal mucosal bleeding time. Intra- and postoperative bleeding scores were subjectively assigned. Blood, spleen, bone marrow, and lymph node aspirates were tested by PCR. Results Bleeding scores in dogs coseroreactive for A. platys and E. canis were higher ( P = .015) than those of seronegative dogs. A. platys DNA was amplified from 7/21 (33%) A. platys seroreactive dogs and from 1 E. canis seroreactive dog; E. canis DNA was amplified from 21/25 (84%) E. canis seroreactive dogs. E. canis DNA was amplified most often from blood, whereas A. platys DNA was amplified most often from bone marrow. Conclusions and Clinical Importance Apparently healthy, free-roaming dogs coseropositive for A. platys and E. canis may have increased intraoperative bleeding tendencies despite normal hemostatic parameters. Future investigations should explore the potential for vascular injury as a cause for bleeding in these dogs. Improved tick control is needed for dogs in Grenada. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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