The Role of Changes in Glucose Metabolism in the Brain in the Formation of Cognitive Impairments in Patients with Remitting and Secondary-Progressive Multiple Sclerosis.

Autor:	Shkil'nyuk, G., Il'ves, A., Kataeva, G., Prakhova, L., Reznikova, T., Seliverstova, N., Stolyarov, I.
Předmět:	GLUCOSE metabolism COGNITION disorder patients MULTIPLE sclerosis MULTIPLE sclerosis diagnosis POSITRON emission tomography STATISTICAL correlation PATIENTS
Zdroj:	Neuroscience & Behavioral Physiology; Jun2013, Vol. 43 Issue 5, p565-570, 6p
Abstrakt:	The mechanism of the development of cognitive impairments in multiple sclerosis (MS) was investigated by studying glucose metabolism at the level of the brain by positron emission tomography (PET). A total of 61 patients with different types of MS were studied. Correlation analysis identified a relationship between cognitive impairments and regional glucose metabolic rate. The authors believe that this may be evidence for an important role for metabolic abnormalities in the gray matter of the brain in the pathogenesis of cognitive impairments in MS. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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