| Autor: |
Hohlfeld, Evan, Geissler, Phillip L. |
| Předmět: |
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| Zdroj: |
Journal of Chemical Physics; 10/28/2014, Vol. 141 Issue 16, p1-5, 5p, 3 Graphs |
| Abstrakt: |
Many forms of cell motility rely on Brownian ratchet mechanisms that involve multiple stochastic processes. We present a computational and theoretical study of the nonequilibrium statistical dynamics of such a many-body ratchet, in the specific form of a growing polymer gel that pushes a diffusing obstacle. We find that oft-neglected correlations among constituent filaments impact steady-state kinetics and significantly deplete the gel's density within molecular distances of its leading edge. These behaviors are captured quantitatively by a self-consistent theory for extreme fluctuations in filaments' spatial distribution. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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