The Chromatin Assembly Factor 1 Promotes Rad51-Dependent Template Switches at Replication Forks by Counteracting D-Loop Disassembly by the RecQ-Type Helicase Rqh1.

Autor: Pietrobon, Violena, Fréon, Karine, Hardy, Julien, Costes, Audrey, Iraqui, Ismail, Ochsenbein, Françoise, Lambert, Sarah A.E.
Předmět:
Zdroj: PLoS Biology; Oct2014, Vol. 12 Issue 10, p1-15, 15p, 1 Black and White Photograph, 1 Chart, 5 Graphs
Abstrakt: : A molecular switch for times of replication stress - Chromatin Assembly Factor 1 helps to protect DNA during recombination-mediated template-switching, favoring the rescue of stalled replication forks by both beneficial and detrimental homologous recombination events. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index