| Autor: |
Dénes, L., Pap, Zsuzsanna, Szántó, Annamária, Hancu, Daniela, Ráduly, G., Pávai, Z. |
| Předmět: |
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| Zdroj: |
Romanian Journal of Functional & Clinical, Macro & Microscopical Anatomy & of Anthropology / Revista Româna de Anatomie Functionala si Clinica, Macro si Microscopica si de Antropologie; 2014, Vol. 13 Issue 3, p273-277, 5p |
| Abstrakt: |
Introduction: Previous reports described two main olfactory systems and several subsystems. The main systems comprise the main olfactory epithelium and the vomeronazal organ. The septal organ is an olfactory subsystem described as an olfactory island surrounded by respiratory epithelium, located in the ventral area of the posterior part of the nasal septum. There are no reports confirming the existence of the human septal organ. Our objective was the identification of the septal organ in human fetuses using morphological methods. Material and method: We used a total of 8 human fetuses and performed the dissection of the nasal area to remove the nasal cavity as a whole. The obtained sections were stained using Alcian blue-van Gieson and PAS staining. To confirm the presence of neural elements we used the primary monoclonal antibodies neuron specific enolase and CD56. Results: Using the histological stains we identified an area of epithelium in the antero-inferior part of the nasal septum that displays the characteristics of the septal organ described in animals: absence of goblet cells, thicker than the surrounding respiratory epithelium, the lamina propria contains PAS+ and alcian-blue+ acini, capillaries, peripheral nerves, and the glands of the lamina propria open through the basement membrane of the epithelium. NSE immunohistochemistry revealed a weak positive signal throughout the septal and turbinate epithelium, and very strong expression in the epithelium of the superior wall, superior part of the septum and superior turbinate, and the vomeronasal organ. CD56 expression was limited to zones known to be chemosensory areas. Conclusions: Histological stains raise the possibility of a chemosensory epithelium that would correspond to the septal organ, but immunohistochemistry did not confirm this aspect. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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