The human bitter taste receptor hTAS2R39 is the primary receptor for the bitterness of theaflavins.

Autor: Toyomi Yamazaki, Miki Sagisaka, Riko Ikeda, Toshiyuki Nakamura, Noriko Matsuda, Takeshi Ishii, Tsutomu Nakayama, Tatsuo Watanabe
Předmět:
Zdroj: Bioscience, Biotechnology & Biochemistry; Oct2014, Vol. 78 Issue 10, p1753-1756, 4p
Abstrakt: The article discusses a study on the responses of hTAS2Rs to 4 major teaflavins based on the theory that the bitterness of theaflavins (TFs) may be sensed through hTAS2R39 and hTAS2R14. hTAS2R and Ga16gust44 were transfected into Flp-In G cells using Lipofectamine 2000 and the cells were incubated for 60 min with 3uM Fluo-8AM. It suggests that the human threshold of bitterness perception can be higher than that of a cell-based assay.
Databáze: Complementary Index