Association Between In-Hospital Mortality and Renal Dysfunction in 186 219 Patients Hospitalized for Acute Stroke in the Emilia-Romagna Region of Italy.
Autor: | Fabbian, Fabio, Gallerani, Massimo, Pala, Marco, De Giorgi, Alfredo, Salmi, Raffaella, Dentali, Francesco, Ageno, Walter, Manfredini, Roberto |
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Předmět: |
MORTALITY risk factors
STROKE-related mortality ANALYSIS of variance CHI-squared test CONFIDENCE intervals HOSPITAL care KIDNEYS RESEARCH methodology RESEARCH funding STATISTICS LOGISTIC regression analysis SEVERITY of illness index ACUTE diseases DATA analysis software DESCRIPTIVE statistics ODDS ratio |
Zdroj: | Angiology; Nov2014, Vol. 65 Issue 10, p906-910, 5p |
Abstrakt: | Using a regional Italian database, we evaluated the relationship between renal dysfunction and in-hospital mortality (IHM) in patients with acute stroke (ischemic/hemorrhagic). Patients were classified on the basis of renal damage: without renal dysfunction, with chronic kidney disease (CKD), and with end-stage renal disease (ESRD). Of a total of 186 219 patients with a first episode of stroke, 1626 (0.9%) had CKD and 819 (0.4%) had ESRD. Stroke-related IHM (total cases) was independently associated with CKD, ESRD, atrial fibrillation (AF), age, and Charlson comorbidity index (CCI). In patients with ischemic stroke (n = 154 026), IHM remained independently associated with CKD, ESRD, AF, and CCI. In patients with hemorrhagic stroke (n = 32 189), variables that were independently associated with IHM were CKD, ESRD, and AF. Renal dysfunction is associated with IHM related to stroke, both ischemic and hemorrhagic, with even higher odds ratios than those of other established risk factors, such as age, comorbidities, and AF. [ABSTRACT FROM PUBLISHER] |
Databáze: | Complementary Index |
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