| Autor: |
Ares, Susana, Quero, José, Diez, Jesus, de Escobar, Gabriella Morreale |
| Předmět: |
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| Zdroj: |
Journal of Pediatric Endocrinology & Metabolism; Nov/Dec2011, Vol. 24 Issue 11/12, p897-902, 6p |
| Abstrakt: |
Context: Hypothyroxinemia in premature neonates may affect long-term neurodevelopment. Objective: This study aimed to examine the effects of hypothyroxinemia of the newborn preterm infants born at 28 - 36 weeks of gestational age (GA) on the neurodevelopment at 4 years of age. Patients: Prospective observational cohort study conducted in Madrid, Spain. Forty-six preterm infants were included in the study. Main Outcome: The effects of the exposure to neonatal hypothyroxinemia on mental development were examined. Results: Using regression analyses we found that neonatal T4 had a positive association with general cognitive index and Verbal index, and neonatal FT4 with general cognitive and Memory indexes at 4 years of age. Conclusions: The exposure to hypothyroxinemia during the neonatal period of late preterm infants may play role in neurodevelopmental delays. Higher T4 level means a trend to higher indexes and low T4 level means a lower neurodevelopmental indexes at 4 years of age. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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