| Autor: |
Nanda, A., Al-Saeed, K., Dvorak, R., Al-Muzairai, I., Al-Sabah, H., Al-Arbash, M., Alsaleh, Q. A. |
| Předmět: |
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| Zdroj: |
Clinical & Experimental Dermatology; May2003, Vol. 28 Issue 3, p301-306, 6p |
| Abstrakt: |
Summary Pemphigoid gestationis (PG) is a rare autoimmune disease of pregnancy. We report a series of 22 cases of PG in Kuwait. They constituted 18% of all the autoimmune bullous diseases registered in our centre over a span of 11 years. PG was observed to be the third most common bullous disease in our region. Ninety-five per cent of the patients were of Arab ethnicity. The clinical features observed in our patients were comparable to those reported elsewhere. Systemic steroids (prednisolone 20–60 mg daily) remained the mainstay of treatment to control the active disease and an optimal dose of 20 mg of prednisolone was maintained throughout the pregnancy and immediate postpartum period. We observed a favourable outcome of pregnancies complicated by PG without any associated maternal or foetal morbidity. Kuwaiti patients with PG were observed to have a predominace of HLA-DR3 and DQ2 antigens. No predominance of HLA-DR4 antigen was observed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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