| Autor: |
Holden, Megan S., Hopper, Andrew, Slater, Laurel, Asmerom, Yayesh, Esiaba, Ijeoma, Boskovic, Danilo S., Angeles, Danilyn M. |
| Zdroj: |
ICAN: Infant, Child & Adolescent Nutrition; Aug2014, Vol. 6 Issue 4, p240-249, 10p |
| Abstrakt: |
Objective. To examine the effect of neonatal morbidity on ATP breakdown in late preterm infants. Study Design. Urinary hypoxanthine concentration, a marker of ATP breakdown, was measured from 82 late preterm infants on days of life (DOL) 3 to 6 using high-performance liquid chromatography. Infants were grouped according to the following diagnoses: poor nippling alone (n = 8), poor nippling plus hyperbilirubinemia (n = 21), poor nippling plus early respiratory disease (n = 26), and respiratory disease alone (n = 27). Results. Neonates with respiratory disease alone had significantly higher urinary hypoxanthine over DOL 3 to 6 when compared with neonates with poor nippling (P = .020), poor nippling plus hyperbilirubinemia (P < .001), and poor nippling plus early respiratory disease (P = .017). Neonates with poor nippling who received respiratory support for 2 to 3 days had significantly higher hypoxanthine compared with infants who received respiratory support for 1 day (P = .017) or no days (P = .007). Conclusions. These findings suggest that respiratory disorders significantly increase ATP degradation in late premature infants. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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