Peptides Stimulate Expression of Signal Molecules in Neuronal Cultures from Animals of Different Age.

Autor: Umnov, R., Lin'kova, N., Khavinson, V.
Předmět:
Zdroj: Bulletin of Experimental Biology & Medicine; Sep2014, Vol. 157 Issue 5, p701-704, 4p
Abstrakt: Molecular mechanisms of the neuroprotective effect of peptide T-33 and cortexin were studied on organotypic cultures of the brain from young and old Wistar rats. The effective concentration of peptide T-33 stimulating proliferative activity of neurons considerably surpassed that of cortexin. Cortexin and peptide T-33 stimulated the expression of serotonin, Ki-67, and vimentin in cells of the brain cortex; peptide T-33 was most effective in this respect. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index