l-Dihydroxyphenylalanine induces melanin production by members of the genus Trichosporon.

Autor: Figueiredo-Carvalho, Maria Helena Galdino, Santos, Fábio B., Nosanchuk, Joshua D., Zancope-Oliveira, Rosely M., Almeida-Paes, Rodrigo
Předmět:
Zdroj: FEMS Yeast Research; Sep2014, Vol. 14 Issue 6, p988-991, 4p
Abstrakt: Melanization of members of the genus Trichosporon is poorly described. In this study, six strains, including two clinical isolates, from four different species ( Trichosporon asahii, T. asteroides, T. inkin, and T. mucoides) were grown in culture media with or without l-dihydroxyphenylalanine ( l- DOPA). Each strain produced a brownish pigment compatible with melanin when cultured in presence of l- DOPA, suggesting that these species are able to produce eumelanin. l-tyrosine was not able to elicit any type of pigment production on cultures. As eumelanin is produced by several fungi during parasitism, this pigment may contribute to Trichosporon virulence. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index