Effects of pulmonary artery perfusion with urinary trypsin inhibitor as a lung protective strategy under hypothermic low-flow cardiopulmonary bypass in an infant piglet model.
| Autor: | Li, W, Wu, X, Yan, F, Liu, J, Tang, Y, Ma, K, Li, S |
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| Předmět: |
MYOCARDIAL revascularization
TRANSLUMINAL angioplasty CARDIOPULMONARY bypass TRYPSIN inhibitors REPERFUSION injury THERAPEUTICS LUNG injury prevention ACADEMIC medical centers ANALYSIS of variance ANIMAL experimentation ENZYME-linked immunosorbent assay HYPOTHERMIA HEALTH outcome assessment PULMONARY artery RESEARCH funding SWINE T-test (Statistics) TREATMENT effectiveness DATA analysis software |
| Zdroj: | Perfusion; Sep2014, Vol. 29 Issue 5, p434-442, 9p |
| Abstrakt: | The article discusses a study on the role of NK-kB in acute lung injury (ALI) induced by deep hypothermia with low flow-cardiopulmonary bypass (DHLF-CPB) in a piglet model and evaluated the protective effect of urinary trypsin inhibitor (UTI) administered by pulmonary perfusion on DHLF-CPB- ALI. The study indicated that DHLF-CPB induced lung injury pulmonary artery (PA) perfusion with UTI led to better lung protection in an infant piglet model. |
| Databáze: | Complementary Index |
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