DISCHARGE OUTCOME IN ADULTS TREATED WITH EXTRACORPOREAL MEMBRANE OXYGENATION.
Autor: | Guttendorf, Jane, Boujoukos, Arthur J., Dianxu Ren, Rosenzweig, Margaret Q., Hravnak, Marilyn |
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Předmět: |
MECHANICAL ventilators -- Evaluation
CHI-squared test EXTRACORPOREAL membrane oxygenation FISHER exact test RESEARCH methodology HEALTH outcome assessment PROBABILITY theory STATISTICS DATA analysis MULTIPLE regression analysis DISCHARGE planning TREATMENT effectiveness CONTINUING education units RETROSPECTIVE studies DATA analysis software DESCRIPTIVE statistics EVALUATION |
Zdroj: | American Journal of Critical Care; Sep2014, Vol. 23 Issue 5, p365-377, 13p, 2 Color Photographs, 1 Diagram, 5 Charts |
Abstrakt: | Background Extracorporeal membrane oxygenation (ECMO) is used for critically ill patients when conventional treatments for cardiac or respiratory failure are unsuccessful. Objectives To describe patient and treatment characteristics and discharge outcome for ECMO patients, determine which characteristics are associated with good (survival) versus poor (death before hospital discharge) outcomes, and compare characteristics of patients with cardiac versus respiratory failure indicating ECMO. Methods Single-center, retrospective review of all adult patients treated with ECMO from 2005 through 2009. Results A total of 212 patients received ECMO for cardiac (n = 126) or respiratory (n = 86) failure. Mean age was 51 (SD, 14.5) years; support duration was 135 (SD, 149) hours. Survival to discharge was 33% overall; 50% for respiratory indication and 21% for cardiac indication patients. Patients with poor outcomes were older (53 vs 47 years, P = .007), more likely to require cardiovascular support before ECMO (99% vs 91%; = .02), and had more transfusions (48 vs 24 units, = .005) and complications (99% vs 87%; P < .001) than did patients with good out- comes. For cardiac patients, older age was associated with poor outcome (poor, 55 vs good, 48 years; P = .01). For respiratory patients, poor outcome was associated with more ventilator days before ECMO (poor, 6 vs good, 3; P = .01), higher peak inspiratory pressure (poor, 39 vs good, 35 cm H |
Databáze: | Complementary Index |
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